Allergy diagnostics

Actuality of allergy diagnostics

Nowadays the prevalence of allergies has become so high that it affects almost every family. The “incorrect” reaction of the body can be caused by both food and contact with even completely ordinary and everyday objects and materials. Most often allergy is caused by dust and pollen. Allergy manifestations also tend to be various – itchy skin, rash, irritating cough, tearing and runny nose. There is often an intestinal disorder. In more several cases swelling on the skin and mucous membranes is observed. Dangerous are such allergic conditions as bronchial asthma and anaphylactic shock which is an especially severe form of pathological allergic manifestation.

In the diagnostics the most important is the analyses of daily observations. Unfortunately, a lot of products and substances, not to mention the composition of the inhaled air, are combined, i.e. not a pure substance. In allergen diagnostics using blood tests (in vitro diagnostics) pure allergens (antigens) are used. They form compounds with corresponding specific antibodies (immunoglobulin E) present in the blood sample (if there are such).

Due to the fact that the spectrum of possible test allergens is currently very wide (hundreds), even in unclear situations, thinking over the choice carefully and taking one step after another consistently, it is possible to clarify the cause of the allergy. This is important because the treatment tactics of different allergens can be very different.

When choosing the probable allergy triggers – allergens, you should think algorithmically, taking into account when, where, how and how often allergy occurs:

• seasonally or without rhythm of the season;
• at a particular location or regardless of location;
• by inhaling, ingesting or contacting with allergen.

In E. Gulbis Laboratory patients’ blood samples (serums) are stored frozen at -20°C at least one month, which allows the investigation to be continued, if necessary, in the light of the results obtained. We recommend initiating an investigation using allergenic panels (summaries) which allows saving money if the potential search direction is initially unclear.

For selection can be used specific IgE allergen panel. In the case of a positive reaction, the allergy will be against some of allergens, contained in the panel.

Dr. Didzis Gavars

Full list of detectable allergens

Contact information:
Payment issues – Sandra Dimante (phone 678801054)
Choice of allergens – Dr. Anda Krišāne (phone 67545052)

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Specific 88 grocery (food) IgG4

Gulbis Laboratory offers a new test to detect IgG₄ antibodies against 88 different food allergens in human serum or plasma.

Test price – EUR 240.-

Food allergies or other forms of intolerance in the human body can develop a variety of adverse reactions. The body’s reaction to a certain product may be immunological sensitivity of IgE and non-IgE, as well as non-immunological intolerance (such as an enzyme deficiency or a reaction to a specific substance).

Immunological reactions to non-IgE meditated foods are commonly referred to as food intolerance. The fact that IgE antibodies are not detected does not meant that the situation is less serious – apparently other immune mechanisms, such as lgG or lgG4 antibodies are involved. IgG or lgG4 – mediated adverse reactions with less severe clinical symptoms are more common (up to 45% of the population). Clinical symptoms occur late – 2 to 72 hours after contact with the substance against which antibodies are formed. The best possible treatment is avoidance of undesirable foods.

The research revealed that:

–          allergic reactions may occur independently of antigen – specific IgE;

–          reduction of IgG antibodies by product exclusion from the nutrition (diet?).

It is recommended that detection of specific IgG or IgG₄ class antibodies is used in patients with unclear clinical symptoms or chronic diseases.

The intolerance of food products is determined by the following parameters:

	Latvian	English	Russian
1	Jēra gaļa	Lamb	Ягненок	F88
2	Liellopu gaļa	Beef	говядинa	F27
3	Cūkas gaļa	Pork	Свинина	F26
4	Cāļa gaļa	Chicken	Kурицa	F83
5	Tītara gaļa	Turkey	индюшкa	F284
6	Menca	Cod	треска	F3
7	Forele	Trout	Форель	F204
8	Lasis	Salmon	Ласось	F41
9	Sardīne	Sardine	Сардина	F61
10	Bute	Plaice	Камбала	F337
11	Tuncis	Tuna	Тунец	F40
12	Garneles	Prawn	Креветки	F24
13	Kazeīns	Casein	Казеин	F78
14	Govs piens	Cow’s milk	Коровье молоко	F2
15	Aitas piens	Sheep’s milk	Овечье молоко	F325
16	Kazas piens	Goat’s milk	Козье молоко	F300
17	Siers Kamambēras (mīkstie sieri)	Camembert	Сыр Камамбер (мягкие сыри)	F82
18	Siers Parmezānas	Parmesan	Сыр Пармезан	F67
19	Siers Rokforas	Roquefort	Сыр Рокфор	F143
20	Olas dzeltenums	Egg yolk	Яичный желток	F75
21	Olas baltums	Egg white	Яичный белок	F1
22	Ābols	Apple	Яблоко	F49
23	Bumbieris	Pear	Груша	F94
24	Ķirši	Cherry	Вишня	F242
25	Plūmes	Plum	Слива	F255
26	Vīnogas	Grape	Виноград	F259
27	Zemenes	Strawberry	Клубника	F44
28	Avenes	Raspberry	Малина	F343
29	Greifrūts	Grapefruit	F209 Грейфрукт	F209
30	Apelsīns	Orange	Апельсин	F33
31	Citrons	Lemon	Лимон	F208
32	Ananass	Pineapple	Ананас	F201
33	Banāni	Banana	Бананы	F92
34	Datele	Date	Финик	F289
35	Kivi	Kiwi	Киви	F84
36	Melone	Honeydew melon	Дыня	F87
37	Mango	Mango	Maнго	F91
38	Persiks	Peach	Персик	F95
39	Olīves	Olive	Маслины	F342
40	Fenhelis	Fennel	Фенхель	F219
41	Gurķi	Cucamber	Огурци	F244
42	Paprika	Bell pepper	Паприка	F46
43	Sparģeļi	Asparagus	Спаржа	F261
44	Spināti	Spinach	Шпинаты	F214
45	Tomāti	Tomato	Помидор	F25
46	Cukīnī	Courgette	Цукини	F118
47	Burkāns	Carrot	Морковь	F31
48	Kartupelis	Potato	Картофель	F35
49	Ķiploks	Garlic	Чеснок	F47
50	Mārrutki	Horseradish	Хрен	F375
51	Redīsi	Red radish	Редиска	F119
52	Selerija	Celery	Селдереи	F85
53	Sīpols	Onion	Лук репчатий	F48
54	Zaļās pupiņas	String bean	Зеленая фасоль	F315
55	Sarkanās pupiņas	Kidney bean	Красная фасоль	F287
56	Zaļie zirnīši	Pea	Зеленый горошек	F12
57	Lēcas	Lentil	Чичивица	F235
58	Sojas pupiņas	Soybean	Соевые бобы	F14
59	Sēnes	Mushroom	Грибы	F212
60	Puķkāposti	Cauliflower	Цветная капуста	F161
61	Kāposti	White Cabbage	капуста	F216
62	Baziliks	Basil	Базилик	F269
63	Karijs	Curry	Kарри	F281
64	Dilles	Dill	Укроп	F277
65	Pētersīļi	Parsley	Мята	F86
66	Piparmētras	Peppermint	Мята	F332
67	Ķimenes	Caraway	Тмин	F265
68	Melnie pipari	Black pepper	Перец черный	F280
69	Timiāns	Thyme	Тимиян	F273
70	Kanēlis	Cinnamon	Корица	F220
71	Kafija	Coffee	Кофэ	F221
72	Kakao	Cocoa	Какао	F93
73	Melnā tēja	Black tea	Черный чай	F222
74	Pārtikas raugs	Baker’s yeast	Дрожжи	F45
75	Griķi	Buckwheat	Гречка	F11
76	Prosa	Millet	Проса	F55
77	Kukurūza	Corn	Кукуруза	F8
78	Rīsi	Rice	Рис	F9
79	Rudzi	Rye	Ржаная мука	F5
80	Kvieši	Wheat	Пшеничная мука	F4
81	Sinepes	Mustard seed	Горчица	F89
82	Sezama sēklas	Sesame	Семена сезама	F10
83	Zemes rieksti	Peanut	Арахис	F13
84	Lazdu rieksti	Hazelnut	фундук (лесной орех)	F17
85	Kokosrieksts	Coconut	Кокосовый орех	F36
86	Mandeles	Almond	Миндаль	F20
87	Pistācijas rieksti	Pistachio	Фисташка	F203
88	Valrieksti	Walnut	Орех грецкий	F256

 

Source: Fintest TM IgG4 Screen 88 ELISA Instructions for Use